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Rachel Tanner

Rachel Tanner, Stipendiary Lecturer in Human Sciences

  • Rachel Tanner

Dr Rachel Tanner is a Lecturer in Human Sciences at Wadham College and Postdoctoral Research Fellow at the Jenner Institute, Nuffield Department of Medicine. She is also Access Officer for the Human Sciences Institute.

She obtained an MA in Biological Sciences from Wadham College and DPhil in Clinical Medicine from St Cross College, supported by the Universities Federation for Animal Welfare (UFAW). 

Rachel’s research interests are immune correlates of protection and the host immune response to tuberculosis vaccination, with a focus on the development of in vitro functional assays that may be applied in preclinical vaccine testing. She is currently a Fellow of VALIDATE; a network focussing on vaccine development for complex intracellular neglected pathogens.

Selected publications

Tanner R, Villarreal-Ramos B, Vordermeier M, McShane H. “The humoral immune response to BCG vaccination.” Front Immunol. 2019; 10:1317. 

Tanner R, Smith SG, van Meijgaarden KE, Giannoni F, Wilkie M, Gabriele L, Palma C, Dockrell HM, Ottenhoff THM, McShane H. “Optimisation, standardisation and harmonisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells.” JIM 2019 June 469:1-10.

Tanner R*, Brennan MJ*, Morris S, Scriba TJ, Achkar JM, Zelmer A, Hokey D, Hoft DF, McShane H, Fletcher HA. “The cross-species mycobacterial growth inhibition assay (MGIA) project 2010-2014.” Clin Vaccine Immunol. 2017 Sep 5;24(9).*denotes shared first authorship. 

Tanner R, O’Shea MK, White AD, Müller J, Harrington-Kandt R……Drakesmith H, Sharpe S, Fletcher HA, McShane H. “The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays.” Sci Rep. 2017 Mar 3; 7:43478. 

Tanner R, McShane H. “Replacing, reducing and refining the use of animals in tuberculosis vaccine research.” ALTEX. 2017;34(1):157-166. 

Tanner R, O’Shea MK, Fletcher HA, McShane H. “In vitro mycobacterial growth inhibition assays: a tool for the assessment of protective immunity and evaluation of vaccine efficacy.” Vaccine. 2016 Sep 7;34(39):4656-4665. 

Tanner R, Kakalacheva K, Miller E, Pathan A, Chalk R, Sander C, Scriba T……Checkley A, McShane H, Fletcher H. “Serum indoleamine 2,3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A.” BMC Infect Dis. 2014 Dec 3;14(1):660.